学术讲座-A measure of concentration robustness in a biochemical reaction network and its application on system identification

讲座题目

A     measure of concentration robustness in a biochemical reaction network and its     application on system identification

讲 座 人

叶剑雄

讲座人

职称、职务

副教授

主持人

许弘雷

讲座类型

R自然科学

讲座对象

全校师生

举办时间

2018/1/12     16:00

□社会科学

举办地点

福建省汽车电子与电驱动技术重点实验室会议室

讲

座

人

简

介

叶建雄，大连理工大学博士，华中科技大学博士后，现为福建师范大学数学与信息学院副教授，当前主持国家自然科学基金一项。

讲座

主要内容

In this talk, we study the concentration robustness of a     microbial metabolism system, in which some mechanistic details are not     clearly known and the true metabolic system needs to be identified from all     possible ones. We give a quantitative index to measure the concentration     robustness of the considered system, which is characterized as the maximum     relative variation in certain entries of steady state caused by the     perturbations of operating parameters. Based on the proposed robustness     index, a minimax dynamic optimization problem is developed for identifying     the kinetic parameters as well as the unknown metabolic mechanisms.